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n (%)
|
% ALT elevated men: > 45 U/L women: > 34 U/L
|
Geometric mean U/L (GSD)
|
Median U/L (IQR)
|
|---|
|
Total
|
15,348 (100.0)
|
18.5
|
28.9 (1.65)
|
28 (21–40)
|
|
Sociodemographic factors
|
|
Age (in years)
|
|
< 35
|
4030 (26.3)
|
17.2
|
27.1 (1.70)
|
26 (19–38)
|
|
35–39
|
1818 (11.9)
|
19.8
|
28.9 (1.70)
|
28 (20–40)
|
|
40–44
|
2200 (14.3)
|
18.5
|
28.2 (1.68)
|
28 (20–40)
|
|
45–49
|
2742 (17.9)
|
19.5
|
30.1 (1.63)
|
29 (22–41)
|
|
50–54
|
2534 (16.5)
|
18.9
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30.6 (1.56)
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30 (23–40)
|
|
≥ 55
|
2024 (13.2)
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18.2
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30.2 (1.57)
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29 (22–39)
|
|
Gender
|
|
Male
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12,013 (78.3)
|
21.6
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32.8 (1.56)
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31 (24–43)
|
|
Female
|
3335 (21.7)
|
7.2
|
18.5 (1.52)
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18 (14–23)
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|
Work-related factors
|
|
Working time system
|
|
Day work
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10,931 (71.2)
|
16.4
|
27.5 (1.66)
|
27 (19–38)
|
|
Shift work
|
4417 (28.8)
|
23.6
|
32.9 (1.59)
|
32 (24–44)
|
|
Occupational group
|
|
Manual worker
|
5447 (35.5)
|
24.0
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32.8 (1.61)
|
32 (24–44)
|
|
Skilled/supervisory worker
|
6453 (42.0)
|
16.8
|
27.3 (1.67)
|
27 (19–38)
|
|
Managerial staff
|
3448 (22.5)
|
13.1
|
26.5 (1.61)
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26 (19–35)
|
|
Lifestyle-related factors
|
|
Smoking statusa
|
|
Non-smoker
|
8735 (56.9)
|
16.6
|
27.6 (1.65)
|
27 (20–38)
|
|
Former smoker
|
3552 (23.1)
|
23.3
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32.2 (1.62)
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32 (23–44)
|
|
Smoker
|
3023 (19.7)
|
18.6
|
29.5 (1.63)
|
29 (21–40)
|
|
Body-mass-index (kg/m2)a
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|
Normal weight (< 25)
|
6138 (40.0)
|
7.8
|
23.1 (1.57)
|
23 (17–30)
|
|
Overweight (25– < 30)
|
6281 (40.9)
|
20.1
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31.5 (1.57)
|
31 (23–42)
|
|
Obesity class I (30– < 35)
|
2150 (14.0)
|
36.4
|
38.0 (1.62)
|
38 (28–53)
|
|
Obesity class II (35– < 40)
|
570 (3.7)
|
40.7
|
39.9 (1.71)
|
39.5 (28–56)
|
|
Obesity class III (≥ 40)
|
207 (1.4)
|
40.1
|
40.5 (1.65)
|
37 (30–56)
|
|
Alcohol consumptiona (drinks per week)
|
|
< 1
|
4297 (28.0)
|
16.5
|
27.1 (1.67)
|
26 (19–37)
|
|
1
|
3911 (25.5)
|
18.4
|
28.2 (1.66)
|
27 (20–39)
|
|
2
|
3294 (21.5)
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18.3
|
29.7 (1.61)
|
29 (22–40)
|
|
≥ 3
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3256 (21.2)
|
21.7
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31.9 (1.61)
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31 (23–43)
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|
Diabetes
|
|
History of diabetes mellitus
|
|
No
|
14,711 (95.9)
|
17.8
|
28.6 (1.64)
|
28 (21–39)
|
|
Yes
|
637 (4.2)
|
35.5
|
37.4 (1.68)
|
36 (27–53)
|
|
Time of examination
|
|
Day of week
|
|
Monday
|
2920 (19.0)
|
18.5
|
28.6 (1.65)
|
28 (21–40)
|
|
Tuesday
|
3717 (24.2)
|
18.5
|
28.7 (1.65)
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28 (20–40)
|
|
Wednesday
|
3170 (20.7)
|
18.6
|
29.1 (1.66)
|
28 (21–40)
|
|
Thursday
|
3074 (20.0)
|
18.9
|
29.5 (1.62)
|
29 (21–39)
|
|
Friday
|
2465 (16.1)
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18.0
|
28.8 (1.66)
|
28 (20–39)
|
|
Weekend
|
2 (0.0)
|
–
|
–
|
–
|
|
Season
|
|
Spring (March–May)
|
4175 (27.2)
|
20.2
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29.9 (1.65)
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29 (21–41)
|
|
Summer (June–August)
|
3589 (23.4)
|
15.1
|
27.2 (1.63)
|
27 (20–37)
|
|
Fall (September–November)
|
3291 (21.4)
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17.2
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28.4 (1.64)
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28 (20–39)
|
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Winter (December–February)
|
4293 (28.0)
|
20.8
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30.0 (1.66)
|
29 (21–41)
|
|
Year
|
|
2013
|
5778 (37.7)
|
17.6
|
28.4 (1.65)
|
28 (20–39)
|
|
2014
|
2471 (16.1)
|
20.2
|
30.3 (1.63)
|
30 (22–41)
|
|
2015
|
1232 (8.0)
|
20.6
|
29.7 (1.61)
|
29 (21–40)
|
|
2016
|
1628 (10.6)
|
20.4
|
29.6 (1.68)
|
29 (21–40)
|
|
2017
|
1897 (12.4)
|
15.5
|
27.8 (1.63)
|
27 (20–38)
|
|
2018
|
2342 (15.3)
|
19.0
|
29.0 (1.67)
|
28 (21–39)
|
- GSD, geometric standard deviation factor, dimensionless, to be multiplied/divided by the geometric mean; IQR, interquartile range
- aMissing values for smoking status (n = 38), BMI (n = 2) and alcohol consumption (n = 590) have been omitted in the table
