Table 4 Univariate analyses of predictive factors associated with 6-week mortality (derivation cohort)
| Parameters | Univariate | |
|---|---|---|
| Odds ratio (95% CI) | P value | |
| Age, years | 1.027 (1.003 1.052) | 0.028 |
| Male sex | 1.021 (0.556 1.875) | 0.947 |
| BMI | 0.900 (0.829 0.977) | 0.012 |
| Systolic blood pressure | 0.959 (0.941 0.976) | 0.000 |
| Hepatocellular carcinoma | 2.647 (1.549 4.522) | 0.000 |
| Heart rate | 1.038 (1.024 1.052) | 0.000 |
| Hemoglobin, g/L | 0.985 (0.976 0.994) | 0.001 |
| Total leukocyte count, × 109/L | 1.171 (1.104 1.242) | 0.000 |
| Platelets, × 109/L | 1.002 (0.998 1.006) | 0.378 |
| Alanine aminotransferase, IU/L | 1.002 (1.001 1.004) | 0.007 |
| Creatinine, μmol/L | 1.002 (1.000 1.004) | 0.038 |
| Sodium, mmol/L | 0.817 (0.777 0.859) | 0.000 |
| Bilirubin, mmol/L | 1.011 (1.008 1.014) | 0.000 |
| Albumin, g/L | 0.893 (0.853 0.935) | 0.000 |
| Cholesterol, mmol/L | 0.396 (0.293 0.535) | 0.000 |
| High-density lipoprotein, mmol/L | 0.007 (0.002 0.020) | 0.000 |
| Low-density lipoprotein, mmol/L | 0.401 (0.266 0.605) | 0.000 |
| International normalized ratio | 17.48 (7.55 40.471) | 0.000 |
| Fibrinogen, g/L | 0.448 (0.283 0.708) | 0.001 |
| Previous bleeding (%) | 1.138 (0.666 1.946) | 0.636 |
| Ascites present (%) | 3.233 (1.724 6.064) | 0.000 |
| Hepatic Encephalopathy present (%) | 7.04 (3.784 13.097) | 0.000 |
| Endoscopic treatment, n (%) | 0.418 (0.233 0.753) | 0.004 |
| TIPS treatment, n (%) | 1.847 (0.609 5.604) | 0.278 |
| PRBC transfusion (%) | 2.033 (1.202 3.441) | 0.008 |
| > 2 PRBC transfusion (%) | 1.248 (0.801 1.591) | 0.066 |
|
QTc prolongation Male (> 450 ms) Female (> 470 ms) | 2.720 (1.604 4.613) | 0.000 |
| Parameters | B | SE | Wals | Odds ratio (95% CI) | P value |
|---|---|---|---|---|---|
| Multivariate analyses: Predictors of 6-week mortality | |||||
| Bilirubin, mmol/L | 0.005 | 0.002 | 6.037 | 1.004 (1.001–1.007) | 0.000 |
| High-density lipoprotein, mmol/L | −2.757 | 0.662 | 17.331 | 0.063 (0.017–0.232) | 0.000 |
| Sodium, mmol/L | −0.112 | 0.031 | 12.851 | 0.894 (0.840–0.950) | 0.000 |
| Hemoglobin, g/L | −0.017 | 0.006 | 7.251 | 0.983 (0.971–0.995) | 0.007 |
| Constant | 16.121 | 4.253 | 14.366 | 10,031,946.4 | 0.000 |